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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
P14866
USC-OGP 2-DE database
:
P14866
P14866
General information about the entry
View entry in simple text format
Entry name
HNRPL_HUMAN
Primary accession number
P14866
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Heterogeneous nuclear ribonucleoprotein L; Short=hnRNP L;.
Gene name
Name=HNRNPL
Synonyms=HNRPL
ORFNames=P/OKcl.14
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1140
:
pI=7.01; Mw=62235
Cross-references
UniProtKB/Swiss-Prot
P14866; HNRPL_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
HNRPL_HUMAN
Primary accession number
P14866
Secondary accession number(s)
A6ND69 A6NIT8 Q9H3P3
Sequence was last modified on
November 25, 2008 (version 2)
Annotations were last modified on
March 15, 2017 (version 184)
Name and origin of the protein
Description
RecName: Full=Heterogeneous nuclear ribonucleoprotein L; Short=hnRNP L;
Gene name
Name=HNRNPL
Synonyms=HNRPL
ORFNames=P/OKcl.14
Encoded on
Name=HNRNPL; Synonyms=HNRPL; ORFNames=P/OKcl.14
Keywords
3D-structure
;
Acetylation
;
Alternative splicing
;
Complete proteome
;
Cytoplasm
;
Direct protein sequencing
;
Isopeptide bond
;
Methylation
;
Nucleus
;
Phosphoprotein
;
Reference proteome
;
Repeat
;
Ribonucleoprotein
;
RNA-binding
;
Ubl conjugation
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
AB044547; BAB18649.1
; -; mRNA
EMBL
AK292115; BAF84804.1
; -; mRNA
EMBL
AC008982; -
; NOT_ANNOTATED_CDS; Genomic_DNA
EMBL
CH471126; EAW56828.1
; -; Genomic_DNA
EMBL
X16135; CAA34261.1
; ALT_INIT; mRNA
CCDS
CCDS33015.1; -. [P14866-1]
; .
CCDS
CCDS33016.1; -. [P14866-2]
; .
PIR
A33616; A33616
; .
RefSeq
NP_001005335.1; NM_001005335.1. [P14866-2]
; .
RefSeq
NP_001524.2; NM_001533.2. [P14866-1]
; .
RefSeq
XP_011525191.1; XM_011526889.1. [P14866-2]
; .
UniGene
Hs.644906; -
; .
PDB
3R27; X-ray
; 2.04 A; A/B=90-180
PDB
3TO8; X-ray
; 1.82 A; A=380-589
PDBsum
3R27; -
; .
PDBsum
3TO8; -
; .
ProteinModelPortal
P14866; -
; .
SMR
P14866; -
; .
BioGrid
109432; 113
; .
DIP
DIP-36355N; -
; .
IntAct
P14866; 39
; .
MINT
MINT-1422378; -
; .
STRING
9606.ENSP00000221419; -
; .
iPTMnet
P14866; -
; .
PhosphoSitePlus
P14866; -
; .
SwissPalm
P14866; -
; .
BioMuta
HNRNPL; -
; .
DMDM
215274006; -
; .
REPRODUCTION-2DPAGE
IPI00027834; -
; .
SWISS-2DPAGE
P14866; -
; .
EPD
P14866; -
; .
MaxQB
P14866; -
; .
PaxDb
P14866; -
; .
PeptideAtlas
P14866; -
; .
PRIDE
P14866; -
; .
DNASU
3191; -
; .
Ensembl
ENST00000221419; ENSP00000221419
; ENSG00000104824. [P14866-1]; .
Ensembl
ENST00000600873; ENSP00000470231
; ENSG00000104824. [P14866-2]; .
Ensembl
ENST00000634237; ENSP00000489244
; ENSG00000282947. [P14866-2]; .
Ensembl
ENST00000634753; ENSP00000489021
; ENSG00000282947. [P14866-1]; .
GeneID
3191; -
; .
KEGG
hsa:3191; -
; .
UCSC
uc060yfy.1; human. [P14866-1]
; .
CTD
3191; -
; .
DisGeNET
3191; -
; .
GeneCards
HNRNPL; -
; .
H-InvDB
HIX0174642; -
; .
HGNC
HGNC:5045; HNRNPL
; .
HPA
CAB016326; -
; .
HPA
HPA051748; -
; .
HPA
HPA052661; -
; .
MIM
164021; gene
; .
MIM
603083; gene
; .
neXtProt
NX_P14866; -
; .
OpenTargets
ENSG00000104824; -
; .
PharmGKB
PA162391389; -
; .
eggNOG
KOG1456; Eukaryota
; .
eggNOG
ENOG410XQHN; LUCA
; .
GeneTree
ENSGT00550000074508; -
; .
HOGENOM
HOG000293298; -
; .
HOVERGEN
HBG105786; -
; .
InParanoid
P14866; -
; .
KO
K13159; -
; .
OMA
PYEGRRM; -
; .
OrthoDB
EOG091G0PR3; -
; .
PhylomeDB
P14866; -
; .
TreeFam
TF354318; -
; .
Reactome
R-HSA-72163; mRNA Splicing - Major Pathway
; .
Reactome
R-HSA-72203; Processing of Capped Intron-Containing Pre-mRNA
; .
SIGNOR
P14866; -
; .
ChiTaRS
HNRNPL; human
; .
GeneWiki
HNRNPL; -
; .
GenomeRNAi
3191; -
; .
PRO
PR:P14866; -
; .
Proteomes
UP000005640; Chromosome 19
; .
Bgee
ENSG00000104824; -
; .
CleanEx
HS_HNRNPL; -
; .
ExpressionAtlas
P14866; baseline and differential
; .
Genevisible
P14866; HS
; .
GO
GO:0005737; C:cytoplasm
; IEA:UniProtKB-SubCell; .
GO
GO:0070062; C:extracellular exosome
; IDA:UniProtKB; .
GO
GO:0030529; C:intracellular ribonucleoprotein complex
; IDA:UniProtKB; .
GO
GO:0016020; C:membrane
; IDA:UniProtKB; .
GO
GO:0005654; C:nucleoplasm
; IDA:UniProtKB; .
GO
GO:0005634; C:nucleus
; IDA:MGI; .
GO
GO:0035770; C:ribonucleoprotein granule
; IDA:UniProtKB; .
GO
GO:0000166; F:nucleotide binding
; IEA:InterPro; .
GO
GO:0097157; F:pre-mRNA intronic binding
; IDA:UniProtKB; .
GO
GO:0003723; F:RNA binding
; IDA:UniProtKB; .
GO
GO:0044212; F:transcription regulatory region DNA binding
; IDA:UniProtKB; .
GO
GO:0010467; P:gene expression
; TAS:Reactome; .
GO
GO:0000398; P:mRNA splicing
; via spliceosome; TAS:Reactome
GO
GO:0000381; P:regulation of alternative mRNA splicing
; via spliceosome; IMP:UniProtKB
GO
GO:0006396; P:RNA processing
; TAS:ProtInc; .
Gene3D
3.30.70.330; -
; 4; .
InterPro
IPR006536; HnRNP-L/PTB
; .
InterPro
IPR012677; Nucleotide-bd_a/b_plait
; .
InterPro
IPR000504; RRM_dom
; .
Pfam
PF00076; RRM_1
; 2; .
SMART
SM00360; RRM
; 3; .
SUPFAM
SSF54928; SSF54928
; 3; .
TIGRFAMs
TIGR01649; hnRNP-L_PTB
; 1; .
PROSITE
PS50102; RRM
; 3; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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